Levels of Evidence - Pyramid

Click on each level in the pyramid to learn more about each level of evidence.

Level I
Level II
Level III
Level IV
Level V

Level I:

Experimental study, randomized controlled trial (RCT)

Sources:

  • Systematic review of RCTs, with or without meta-analysis
  • Critically Appraised Topic (Evidence synthesis)
  • Critically Appraised Individual Topics (Article Synopsis)

Level II:

Quasi-experimental Study
Systematic review of a combination of RCTs and quasi-experimental, or quasi-experimental studies only, with or without meta-analysis

Sources:

  • Systematic review of RCTs, with or without meta-analysis
  • Critically Appraised Topic (Evidence synthesis)
  • Critically Appraised Individual Topics (Article Synopsis)

Level III:

Non-experimental study
Systematic review of a combination of RCTs, quasi-experimental and non-experimental, or non-experimental studies only, with or without meta-analysis
Qualitative study or systematic review, with or without meta-analysis

Sources:

  • Systematic review of RCTs, with or without meta-analysis
  • Critically Appraised Topic (Evidence synthesis)
  • Critically Appraised Individual Topics (Article Synopsis)

Level IV:

Opinion of respected authorities and/or nationally recognized expert committees/consensus panels based on scientific evidence

Sources:

Clinical practice guidelines

Consensus panels

Level V:

Based on experiential and non-research evidence

Sources:

  • Literature reviews
  • Quality improvement, program or financial evaluation
  • Case reports
  • Opinion of nationally recognized expert(s) based on experiential evidence
Adapted from: Dearholt, S. & Dang, D., (2012). Johns Hopkins Nursing Evidence-based Practice : Models and Guidelines. Sigma Theta Tau International.